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Simple blood test to improve ovarian cancer diagnosis
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IANS | 18 Feb, 2020
Researchers have developed a simple blood test that measures the body's
own immune response to improve diagnosis of ovarian cancer.
The
study, published in the journal Scientific Reports, found that testing
for a specific immune biomarker allows clinicians to identify whether
growths on the ovaries are cancerous or not, without the need for tests
like the MRI scans or ultrasounds.
Ovarian cancer is one of the
most common gynaecologic cancers, with the highest mortality rate. About
300,000 new cases are diagnosed globally each year, with an estimated
60 per cent of women dying within five years after diagnosis.
"Our
new test is as accurate as the combined results of a standard blood
test and ultrasound. This is especially important for women in remote or
disadvantaged communities, where under-resourced hospitals may not have
access to complex and expensive equipment like ultrasound machines or
MRI scanners," said study senior author Magdalena Plebanski from the RMIT University in Australia.
"It
also means patients with benign cysts identified through imaging could
potentially be spared unnecessary surgeries," Plebanski added.
According
to the researchers, the test could be an important diagnostic tool for
assessing suspicious ovarian growths before operations.
"This
study looked at women with advanced ovarian cancer, but we hope further
research could explore the potential for adding this biomarker to
routine diagnostic tests at earlier stages of the disease," Plebanski
said.
The study used an immune marker for inflammation (IL-6)
together with cancer markers to detect epithelial ovarian cancer in
blood.
According to the researchers, results were validated across two separate human trial cohorts.
"Every day in Australia, four women are diagnosed with ovarian cancer and three will die from the disease," Plebanski said.
"Developing
tests that are simpler and more practical may help get more women to
hospital for treatment more effectively, with the hope that survival
rates will improve," Plebanski concluded.
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